The “LM” style Linear Microdialysis Probe is intended for microdialysis of soft tissues such as dermis, subcutaneous tissue, muscle, adipose, peritoneal organs, and other tissues.

The LM probe offer a small profile (320 µm OD) and consists of a short length of hollow dialysis fiber attached to smaller diameter flexible medical grade plastic inlet and outlet tubes.  The microdialysis membrane is the larger diameter and so is directly in contact with the tissue.  Via an internal fiber that strengthens the probe and extends beyond the probe tubing, the probe can be “threaded” into the tissue.   A plug seals the end of the probe from which the fiber skeleton extends. This plug keeps body fluids from entering the probe during surgery and is cut off before the probe is connected to a syringe pump and perfused.

Linear microdialysis probes are available with either 5 mm or 10 mm active lengths of dialysis membrane. Custom probes with other membrane lengths are also available.  “DL” probes may be a stock alternative to LM custom probes.

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Name LM-5, Linear Microdialysis Probe, 5mm membrane
LM-10, Linear Microdialysis Probe, 10mm membrane 
Part Number MD-2005, LM-5
MD-2000, LM-10 
Tubing Flexible, 320µm OD, inert biocompatible plastic, 25cm on each side of membrane for LM-5, 30cm on each side of membrane for LM-10


Probe Volume 12.9µL total for LM-5
15.7µL total for LM-10 
Use Can be used to dialyze soft tissues such as dermis, subcutaneous, muscle, liver and pancreas.  Small OD makes it ideal for small, sensitive targets. Internal guide fiber eases implantation and enhances durability.  Can be implanted with 25G needle


Membrane PAN. 30KDa MWCO, 320µm OD
Ask us about customized probes 




OD 320 µm ID 240 µm


OD 218 µm ID 180 µm

“LM” Linear Microdialysis Probes