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”IBR” Combination Brain Microdialysis and Infusion probes
The “IBR” style microdialysis probe facilitates infusing a treatment directly to the area being dialyzed. Unlike when administering a treatment systemically or via retrodialysis through a microdialysis probe membrane, when this probe is used, you can both target your treatment with anatomical specificity and know exactly how much drug you have administered. This can also address solubility or molecular weight issues of retrodialysis. The infusate exits the infusion cannula at the distal tip of the microdialysis membrane just outside the membrane lumen.
Overview
Name | IBR-2, Combination Infusion and Microdialysis Probe, 2mm membrane* IBR-4, Combination Infusion and Microdialysis Probe, 4mm membrane**
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Part Number | MD-2262, IBR-2, 2mm membrane MD-2264, IBR-4, 4mm membrane
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Cannula | Coated fused silica
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Probe Volume | 2.1 to 2.3 µL (IBR-2 or IBR-4)
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Infusion Cannula | Coated fused silica
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Use | Use with optional intracerebral guide cannula, or mount directly on skull using acrylic cement. Commonly used for rats, hamsters, and guinea pigs. Non-metallic, can be used for NMR imaging.
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Membrane | PAN. 30KDa MWCO, 320µm OD
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Dimensions | Membrane
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OD 320µm | ID 220µm |
Infusion Cannula Tip
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OD 105µm | ID 40µm | |
Infusion Cannula Swept Volume
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0.56 µL | ||
Probe Cannula Diameter
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OD 510µm | ID 360µm | |
Probe Cannula Length
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15 mm | ||
Probe Cannula Length when in BASi guide cannula
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10 mm | ||
Head Diameter
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6.4mm | ||
Tubing Inlet/Outlet
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OD 635µm | ID 254µm |
* single customization only, ** cannot customize