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The “IBR” style microdialysis probe facilitates infusing a treatment directly to the area being dialyzed.  Unlike when administering a treatment systemically or via retrodialysis through a microdialysis probe membrane, when this probe is used, you can both target your treatment with anatomical specificity and know exactly how much drug you have administered.  This can also address solubility or molecular weight issues of retrodialysis. The infusate exits the infusion cannula at the distal tip of the microdialysis membrane just outside the membrane lumen.

Overview

Name IBR-2, Combination Infusion and Microdialysis Probe, 2mm membrane*
IBR-4, Combination Infusion and Microdialysis Probe, 4mm membrane**

 

Part Number MD-2262, IBR-2, 2mm membrane
MD-2264, IBR-4, 4mm membrane

 

Cannula Coated fused silica

 

Probe Volume 2.1 to 2.3 µL (IBR-2 or IBR-4)

 

Infusion Cannula Coated fused silica

 

Use Use with optional intracerebral guide cannula, or mount directly on skull using acrylic cement. Commonly used for rats, hamsters, and guinea pigs.  Non-metallic, can be used for NMR imaging.

 

Membrane PAN. 30KDa MWCO, 320µm OD

 

Dimensions Membrane

 

OD 320µm ID 220µm
Infusion Cannula Tip

 

OD 105µm ID 40µm
Infusion Cannula Swept Volume

 

0.56 µL
Probe Cannula Diameter

 

OD 510µm ID 360µm
Probe Cannula Length

 

15 mm
Probe Cannula Length
when in BASi guide cannula

 

10 mm
Head Diameter

 

6.4mm
Tubing Inlet/Outlet

 

OD 635µm ID 254µm

* single customization only, ** cannot customize

IBR Combination Infusion & Microdialysis BRain Probe