”IBR” Combination Brain Microdialysis and Infusion probes

The “IBR” style microdialysis probe facilitates infusing a treatment directly to the area being dialyzed. Unlike when administering a treatment systemically or via retrodialysis through a microdialysis probe membrane, when this probe is used, you can both target your treatment with anatomical specificity and know exactly how much drug you have administered. This can also address solubility or molecular weight issues of retrodialysis. The infusate exits the infusion cannula at the distal tip of the microdialysis membrane just outside the membrane lumen.

Overview

Name IBR-2, Combination Infusion and Microdialysis Probe, 2mm membrane* IBR-4, Combination Infusion and Microdialysis Probe, 4mm membrane** Part Number MD-2262, IBR-2, 2mm membrane MD-2264, IBR-4, 4mm membrane Cannula Coated fused silica Probe Volume 2.1 to 2.3 µL (IBR-2 or IBR-4) Infusion Cannula Coated fused silica Use Use with optional intracerebral guide cannula, or mount directly on skull using acrylic cement. Commonly used for rats, hamsters, and guinea pigs. Non-metallic, can be used for NMR imaging. Membrane PAN. 30KDa MWCO, 320µm OD Dimensions Membrane OD 320µm ID 220µm Infusion Cannula Tip OD 105µm ID 40µm Infusion Cannula Swept Volume 0.56 µL Probe Cannula Diameter OD 510µm ID 360µm Probe Cannula Length 15 mm Probe Cannula Length when in BASi guide cannula 10 mm Head Diameter 6.4mm Tubing Inlet/Outlet OD 635µm ID 254µm * single customization only, ** cannot customize IBR Combination Infusion & Microdialysis BRain Probe