The “IBR” style microdialysis probe facilitates infusing a treatment directly to the area being dialyzed.  Unlike when administering a treatment systemically or via retrodialysis through a microdialysis probe membrane, when this probe is used, you can both target your treatment with anatomical specificity and know exactly how much drug you have administered.  This can also address solubility or molecular weight issues of retrodialysis. The infusate exits the infusion cannula at the distal tip of the microdialysis membrane just outside the membrane lumen.

Overview

Name	IBR-2, Combination Infusion and Microdialysis Probe, 2mm membrane* IBR-4, Combination Infusion and Microdialysis Probe, 4mm membrane**
Part Number	MD-2262, IBR-2, 2mm membrane MD-2264, IBR-4, 4mm membrane
Cannula	Coated fused silica
Probe Volume	2.1 to 2.3 µL (IBR-2 or IBR-4)
Infusion Cannula	Coated fused silica
Use	Use with optional intracerebral guide cannula, or mount directly on skull using acrylic cement. Commonly used for rats, hamsters, and guinea pigs.  Non-metallic, can be used for NMR imaging.
Membrane	PAN. 30KDa MWCO, 320µm OD
Dimensions	Membrane	OD 320µm	ID 220µm
	Infusion Cannula Tip	OD 105µm	ID 40µm
	Infusion Cannula Swept Volume	0.56 µL
	Probe Cannula Diameter	OD 510µm	ID 360µm
	Probe Cannula Length	15 mm
	Probe Cannula Length when in BASi guide cannula	10 mm
	Head Diameter	6.4mm
	Tubing Inlet/Outlet	OD 635µm	ID 254µm

* single customization only, ** cannot customize

IBR Combination Infusion & Microdialysis BRain Probe